Current lab members

Shukry Habib pursued his undergraduate studies in biology at the Technion in Israel. He received his Master’s degree in Biochemistry from Tel Aviv University in Israel under the supervision of Prof. Abdussalam Azem. Shukry completed his graduate doctorate studies (Dr. rer. nat) in Biochemistry under the supervision of Prof. Walter Neupert and Prof. Doron Rapaport at the Institute of Physiological Chemistry, LMU in Munich, Germany. His graduate studies focused on the biogenesis of mitochondrial membrane proteins. Shukry became a postdoctoral fellow in the lab of Prof. Roel Nusse at Stanford University, California. There, incorporating advanced imaging techniques and bioengineering, he established a novel system to study asymmetric cell division of mammalian stem cells. During this project, Shukry joined the Janelia (HHMI) visitor program and worked together with the group of the Nobel prize laureate Dr. Eric Betzig to visualize cell division at super-resolution under real time. Currently Shukry is a principal investigator at the Centre for Stem Cells and Regenerative Medicine at King's college London.

Shukry has received numerous awards and honors including: Minerva fellowship (Max-Plank Society), EMBO fellowship, DFG fellowship and Siebel scholar. Recently he was awarded the Sir Henry Dale fellowship (Wellcome Trust and Royal Society, UK), one of the most prestigious awards for young investigators.

Soon Seng Ng  completed his PhD in Biophysics at Nanyang Technological University, Singapore. The primary aim of his PhD project is to investigate the role of biophysical signals on cardiac and cartilage regeneration. After PhD completion, he did his first post-doctoral training at Stanford University, USA, to develop artificial liver tissue using primary fetal liver cells and hydrogel technology for drug screening, HCV disease modelling, and transplantation. He then moved to King’s College London, UK, to explore the therapeutic potential of induced pluripotent stem cell (iPSC) technology on liver therapy. He has successfully engineered liver organoids by modulating the niche factors of the iPSC using a precise bottom-up fabrication approach for culture model development. Currently, Soon Seng is working on the Wnt-modulated liver tissue engineering project funded by UKRMP.

Yoshishisa Okuchi graduated from Faculty of Medicine at Kyoto University, Japan, and earned his MD degree in 2006. He worked as a gastrointestinal surgeon for six years, especially focusing on colorectal cancer remedy including chemotherapy. Then, Yoshishisa started his research about intestinal tumorigenesis under the supervision of Prof. Michiyuki Matsuda at Kyoto University, who was one of the most famous researchers about FRET biosensor and live imaging. Especially, Yoshishisa was interested in the relationship between aging and tumorigenesis. Thus, he tried to distinguish aged cells from non-aged ones in the mouse small intestine by using a two-photon excitation microscopy, and analyzed their gene expression profiles. His research is the first one to visualize both aged and non-aged cells and to examine the effect of aging on intestinal tumorigenesis at single cell level. Yoshishisa was awarded the PhD degree in 2016 and currently he is a postdoc fellow in the Habib Lab.

Rebecca Contrudi Rebecca Condruti attends Arizona State University and will graduate with her Bachelor's degree in Microbiology in 2020. She has been an undergraduate researcher in Dr. Xuan Wang's lab at ASU studying the role of drug efflux transporters during ethanol fermentation. Her projects include constructing a mutant plasmid library to examine the small multidrug transporter, SugE, as well as exploring the role of quorum sensing genes in cell-to-cell signaling under fermentation conditions. Currently Rebecca is a visiting student in the Habib lab and study the role of mitochondrial segregation during asymmetric stem cell division. 

Zaynab Butt is an undergraduate student, currently studying for a BSc in Biomedical Science at King’s College London. She is joining the Habib lab as part of an Extended Research Project in Genetics, in her final year of study. Currently Zaynab investigates the ability of localised Wnt signals to orient asymmetric cell division of skeletal stem cells in 3D scaffold. 

Wladislaw Stroukov acquired a BSc in Molecular Medicine and MSc in Biochemisty & Biophysics at the University of Freiburg in Germany. He completed an ERASMUS placement at the UCL Institute of Child Health in London where he focussed on targeted gene correction of perforin deficiency in patients with hemophagocytic lymphohistiocytosis. During his Master’s thesis he worked on the development of a biocompatible hydrogel coating for drug delivery at neural micro-electrode interfaces. In parallel he investigated the protein trafficking to the primary cilium. Currently, Wlad is enrolled in the Wellcome Trust 4-Year Phd Programme at the CSCRM and performing a rotation in the Habib Lab. He studies the role of  glutamatergic signalling in niche-stem cell interaction.

Talha Hubeen obtained his Bchelor in Dental Surgery (BDS) in 2011 from National University of Science and Technology, Pakistan (NUST) followed by a four year specialty training in Orthodontics, mainly treating patients with orofacial defects or recessions after cancer treatments. During his residency, he served as a Research Intern at a few Pathology and Cancer Therapeutics Lab (Pakistan) to learn Basic Tissue Culture techniques. Talha joined the Centre of Craniofacial and Stem cell Biology as a Masters Student in Regenerative Dentistry from September 2018 with an aim to understand stem cells and their therapeutic potential. He is currently a master student in the Habib lab and studies the effect of immoblised Wnt proteins on craniofacial bone regeneration.

Joshua Reeves graduated in July 2017 from the University of Nottingham with an MSci in Biochemistry and Biological Chemistry. Between his second and third years, he was a research intern at the Centre for Biomolecular Sciences in Nottingham investigating chlorotoxin as a drug-delivery conjugate, affirming his interest in molecular and cellular biology. He then returned to the Centre for Biomolecular Sciences in his Master’s year to carry out a research project on the mechanism of silver-based antibiotic resistance in drug-resistant bacteria. Currently Josh is a research technician in the Habib Lab. 

Sergi Junyent Espinosa earned his Bachelor’s degree in Biology from the University of Barcelona (Barcelona, Spain). As part of his Bachelor, Sergi completed an Erasmus Training Internship in the Institute of Molecular Genetics of the ASCR (Prague, Czech Republic), where he studied the role of ORMDL3 in the Mast Cell FceRI signalling pathway. Then, in 2016 Sergi completed an MSc degree in Biomedical Research at Pompeu Fabra University (Barcelona, Spain). His MSc thesis was performed at the Reprogramming and Regeneration group, Centre for Genomic Regulation (CRG), where he studied the role of the Wnt/β-catenin pathway in the control of pluripotency in mouse Embryonic Stem cells. Sergi is currently a PhD student in the Habib Lab. 

Tung-Jui Trieu received his BSc in Life Sciences, and his Master’s degree in Cell Biology from Pierre & Marie Curie University - Paris VI, France. Before joining the Habib Lab, he completed an internship at the Department of Infection and Epidemiology within the Institut Pasteur in Paris, under the supervision of Prof. Fabrice Chrétien. His studies focused on the impact of sepsis on skeletal muscle and on the niche of satellite cells. He also investigated the regeneration capacities of skeletal muscle during sepsis. Currently Tung-Jui is a PhD student in the Habib Lab.

James Szczerkowki acquired an MSci in medicine from Lancaster University England, 2015. Where he undertook two projects: in his third year project he employed confocal techniques to assess the sub-cellular localisation patterns of potential glutamate pathway components; in his fourth year project he utilised scanning and transitional electron microscope techniques, with the goal of reaffirming the feasibility of using cultivated oral mucosal stem cells as a transplantable corneal epithelial substitute, for use in ocular surface disease.

Most recently Jamie has taken a PhD position in the Habib Lab, in order to study the molecular mechanism of asymmetric stem cell division

Blaise Louis completed her undergraduate studies in Biomedical Sciences at Royal Holloway University of London. During her final year she completed a research project focussing on the regulation of the behavior of satellite cells, specifically the mechanisms that maintain their state of quiescence, regulate their activation and determine the fate of their progeny. Shortly after graduating she joined Professor Fiona Watt’s lab in the Centre for Stem Cells and Regenerative Medicine at King’s College London as a Research Technician. She is currently a member of the Habib Lab, assisting with Cell culture, Histology and general lab maintenance.  

Adam Syanda completed an integrated Master’s degree in Biomedical Science at Manchester Metropolitan University, UK. During the course, he carried out an industrial placement year at the GlaxoSmithKline site in Worthing, where he was a part of the process support team. In his penultimate year of studies, he investigated the role of plasminogen activator inhibitor-1 (PAI-1) in renal fibrosis. In his final year, he shifted his focus to studying macrophage phenotype in the setting of renal acidosis, a condition associated with chronic renal disease. After completion of his studies, Adam worked at ProImmune Ltd, an immunology contract research organisation, where he researched the immunogenicity of drug candidates using cellular assays. Currently, Adam is taking part in a BBSRC-funded London Interdisciplinary Doctoral Program (LIDo) and is carrying out research in the Habib lab to study the role of Wnt in liver regeneration.

Alumni members: 

Raymond O: exchange student (July 2017)

Clare Garcin: Research Associate (December 2017)

Geraldine Jowett: Wellcome Trust PhD Student (April 2017)

Anushka Bahrgava: MSc KCL Genetics project (March 2017)

Anna Worsley: LIDo PhD rotation student (January 2017)

Molly Lowndes- Research Associate (December 2016)

Deniz Kent- KBI PhD rotation student (December 2016)

Alice Santambrogio-MSc Erasmus student (February 2016) 

© 2016 by Shukry Habib.

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